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Vitamin D supplementation reduces levels of Ki67 in prostate cancer cells

Posted on: April 2, 2012   by  Vitamin D Council


New research presented at the AACR annual meeting 2012 held March 31st-April 4th demonstrates that vitamin D may slow the growth of prostate cancer.

Reinhold Vieth, Ph.D., professor at the University of Toronto in Toronto, Ontario, Canada published the study in which 66 men scheduled for radical prostatectomy were randomly assigned to receive daily vitamin D doses of 400, 10,000 or 40,000 IU for 3-8 weeks before surgery.

Calcitriol levels increased in the prostate daily, with each dose of vitamin D, the highest levels found among the 40,000 IU group.

The authors found that the higher the vitamin D levels, the lower prostate levels of Ki67, a protein which indicates prostate cancer cell growth.

Dr Veith calls for further research in which patients diagnosed with prostate cancer will be randomly assigned to take either a placebo or high dose vitamin D supplement.


American Association for Cancer Research (AACR) (2012, March 31). Oral vitamin D supplements reduced levels of Ki67 in prostate cancer cells. ScienceDaily. Retrieved July 16, 2012, from http://www.sciencedaily.com­/releases/2012/03/120331151134.htm

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