A new case-control study published by the journal PLoS One found vitamin D deficiency was highly prevalent among children with IBS.
Irritable bowel syndrome (IBS) is a gastrointestinal disorder that causes cramping, gas, bloating, diarrhea and/or constipation. Although the etiology is unknown, doctors believe a combination of genetic predisposition and stress may contribute to the onset of IBS.
Vitamin D has shown to play an important role in the development and treatment of IBS among adults; however, this relationship has yet to be evaluated among children or adolescents.
Researchers recently conducted a case-control study, hypothesizing that vitamin D status would remain similar between pediatric patients with IBS and healthy controls. A total of 55 patients with IBS and 116 health controls (ages 16.5 and 14.6, respectively) were included in the analysis. Vitamin D levels below 22 ng/ml (50 nmol/l) were considered deficient, and levels of 30 ng/ml or greater were considered sufficient. The primary psychosomatic indices of IBS included depression, anxiety and migraines.
Here is what the researchers found:
The researchers concluded,
“Pediatric patients with IBS had significantly lower 25(OH)D concentration compared to controls despite having similar mean BMI values as controls.”
“Monitoring for vitamin D deficiency should be part of the routine care for patients with IBS. Randomized control trials are warranted to determine the role of adjunctive vitamin D therapy in pediatric IBS.”