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Vitamin D receptor sites on the human genome

Posted on: December 20, 2011   by  John Cannell, MD


People ask me all the time why I say vitamin D regulates over 2,000 genes, about one tenth of your genes. How many genes does vitamin D regulate? Dr. Sreeram Ramagopalan and colleagues at Oxford University published the latest and best paper on the subject.

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3 Responses to Vitamin D receptor sites on the human genome

  1. [email protected]

    As someone who has spent his entire life in South Texas, I remember having a “dues” to pay every spring wherein I experienced a sunburn, once. Shed a layer of skin, and then I was immune to the sun for the rest of the season.
    In the last 3+ years I have been aggressive about Vitamin D in my pharmacy practice, and followed my own blood level, insuring a range always between 50 and 100. I may spend 4 or 5 days in a row inside, doing 13 hour shifts in the pharmacy. Then, I’ll spend sunup to sundown outside, working on projects in the sun, or else conducting archery tournaments – I have never burned, even once, regardless of spending 10 or 12 hours of central Texas sun intensity in the middle of the summer, since bringing my vitamin D into therapeutic range. Never shed a layer of skin, never used sunscreen, a very interesting “side effect” of adequate vitamin D levels in my mind.

  2. [email protected]

    I had been taking D3 for several months while in Alaska and when I went to Desert Hot Springs California and spent a couple weeks 6 hours a day working on my roof project with no sun screen and no shirt and no sunburn . Three years earlier I was out for 10 min in the sun painting the house without sunscreen and got sunburned .

  3. Brant Cebulla
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