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Vitamin D may protect against certain inflammatory compounds in polycystic ovary syndrome

Posted on: July 15, 2014   by  Will Hunter


A new study from Journal of Clinical Endocrinology and Metabolism has found that in polycystic ovary syndrome, vitamin D may have a protective effect against the actions of inflammatory compounds called advanced glycation end products.

Polycystic ovary syndrome (PCOS) is a disorder that is characterized by high levels of androgens (hormones that control male characteristics) and irregular or rare ovulation.

Normally, ovulation occurs when a follicle containing the egg grows and then releases the egg once it reaches maturity. In women with PCOS, the follicle does not release the eggs which begin to accumulate in the ovaries, resulting in the formation of small, benign cysts. PCOS affects 5% to 10% of women of reproductive age.

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1 Response to Vitamin D may protect against certain inflammatory compounds in polycystic ovary syndrome

  1. Rita and Misty

    Will, I commend you on a great article. 🙂

    Along the same vein, here is a link to an article that discusses reproduction later in life is a marker for longevity in women.


    Nine years ago, I entered into what my physician termed “early idiopathic menopause.” I was just barely 40 at the time. My own mom entered menopause at age 58. I was given a script for estrogen, progesterone and testosterone. These did not help me. I felt truly ill. For me, there was absolutely no joy in daily living. To my doctor’s credit, she did indeed test my 25(OH)D level, and she marveled at my results of 32 ng/ml. She said few women in Connecticut had such a wonderful level.

    Little did I know at the time that I was actually deficient.

    By happenstance, destiny or serendipity, at age 46 I landed here on the Vitamin D Council website. And it is here that I learned about optimal 25(OH)D levels….

    Upon correcting my vitamin D deficiency, my menses returned–as well as my good health and my vitality. Now heading towards 50, I have never (ever) felt better! Really. Truly.

    Not that I would ever envision pregnancy for myself at age 50, but I’m certainly glad that my menses returned, especially after reading that article on longevity being tied into later age at menopause.

    There is perhaps no way to definitely prove it, but I link the return of my menses to my higher 25(OH)D level.

    Both my mom and grandmother went thru menopause at age 58. Why would any sane physician think that menopause at age 40 would have been okay for me?

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