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Vitamin D deficiency linked to poor lung function in asthmatic children?

Posted on: July 17, 2012   by  Vitamin D Council


Research published in the American Journal of Respiratory and Critical Care Medicine found that vitamin D deficiency may be linked with poor lung function in children with asthma.

The study examined 1,024 participants from the Childhood Asthma Management Program who had persistent asthma and were currently being treated with inhaled corticosteroids.

At the time of enrollment, the participants 25(OH)D levels were assessed. The children were organized in groups based on their recorded D levels; vitamin D sufficient (>30 ng/ml), insufficient (20-30 ng/ml), and deficient (<20 ng/ml).

The researchers found that, when compared to the other two groups, participants in the deficient group were more likely to have worse pre-bronchodilator forced expiratory volume (FEV1) scores after treating with corticosteroids for 12 months.

The lead author of the study, Ann Chen Wu, M.D., M.P.H. concluded with:

“Our study is the first to suggest that vitamin D sufficiency in asthmatic children treated with inhaled corticosteroids is associated with improved lung function. Accordingly, vitamin D levels should be monitored in patients with persistent asthma being treated with inhaled corticosteroids.”


Wu AC, et al. The Effect of Vitamin D and Inhaled Corticosteroid Treatment on Lung Function in Children. American Journalof Respiratory and Critical Care Medicine. July 2012.

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