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Vitamin D deficiency linked to allergy in infants

Posted on: March 8, 2013   by  Vitamin D Council


One year old infants with vitamin D deficiency are more likely to have a food allergy when compared to infants with higher vitamin D levels, according to research conducted at the Murdoch Childrens Research Institute (MCRI) in Melbourne, Australia.

Katrina Allen, PhD, and colleagues assessed vitamin D status and skin prick test results from 577 infants.

They found that infants of Australian-born parents, but not of parents overseas, with vitamin D insufficiency (<20 ng/ml) were more likely to have a peanut and/or egg allergy than were those with sufficient vitamin D levels. Furthermore, among infants with Australian-born parents, those with levels <20 ng/ml were more likely to have two or more food allergies rather than a single allergy.

The researchers conclude,

“These results provide the first direct evidence that vitamin D sufficiency may be an important protective factor for food allergy in the first year of life.”


Allen KJ  Koplin JJ, Ponsonby A, Gurrin LC, Wake M, et al. Vitamin D insufficiency is associated with challenge-proven food allergy infants. The Journal of Allergy and Clinical Immunology. March 2013.

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