Women diagnosed with takotsubo cardiomyopathy, a condition that causes sudden temporary weakening of the muscles of the heart, have a high prevalence of vitamin D insufficiency, according to research published in the Journal of Clinical Endocrinology and Metabolism.
Takotsubo cardiomyopathy, which is typically caused by acute emotional stress, has been nicknamed “stress cardiomyopathy” or “broken-heart syndrome.” Takotsubo cardiomyopathy is a recognized cause of acute heart failure, which occurs when the heart cannot sufficiently pump to maintain blood flow to the whole body.
Amit Dante, MD, and colleagues identified patients diagnosed with takotsubo cardiomyopathy from April 2009 through January 2011.
Of twenty-five patients diagnosed with takotsubo cardiomyopathy, 68% had low vitamin D levels (<30 ng/ml). Comparing the women with low vitamin D and those with higher vitamin D, the researchers found that those with vitamin D insufficiency had slightly worse heart failure than those with sufficient vitamin D levels (p<.05).
Dande AS, Sena SF, Wasserman HS, Warshofsky MK, Belsky JL. Prevalence and consequences of vitamin D insufficiency in women with takotsubo cardiomyopathy. Clinical Endocrinology & Metabolism. March 2013.