My understanding is that the optimal level of 1,25 Di-Hydroxy Vitamin D (Calcitrol / Active D) is 50ng/ml. What is the optimal range for 25-Hydroxy Vitamin D (storage D)? Is there an optimal ratio between the two?

Asked by  Sheldon on November 11, 2014

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  • Sheldon
    Participant
     Sheldon on

    See title

    Answered by  Sheldon on

  • IAW
    Participant
     IAW on

    Sheldon you have it backwards. The optimal range for 25 Hydroxy Vitamin D (storage) is 50 ng/ml as promoted be the Vitamin D Council. Anything below is really not acceptable and there is an upper end of the range of 100 ng/ml. This is the only test you should rely on to measure your vitamin D levels.
    Levels of 1,25-dihyroxyvitamin D have little or no relationship to vitamin D stores so there is no optimal ratio.

    Answered by  IAW on

    • Sheldon
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       Sheldon on

      How can active and storage Vitamin D not be related? Doesn’t storage D get depleted by converting into active D? What is the optimal range of active D?

      Answered by  Sheldon on

    • IAW
      Participant
       IAW on

      http://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=140
      The article is titled ” Don’t routinely measure 1,25-dihydroxyvitamin D unless the patient has hypercalcemia or decreased kidney function.” It is a good article and should answer your questions.

      Answered by  IAW on

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