I have high calcitriol, and my endocrinologist doesn't think it's caused by vitamin D deficiency. My 25-OH-D level is 30 and my 1,25-dihydroxyvitamin D is 140; calcium is normal. Could a CYP27B1 gene mutation cause this? What could be other causes of this?

Asked by  vivavintageapparel03132800 on July 5, 2015

Answers
  •  vivavintageapparel03132800 on

    See title

    Answered by  vivavintageapparel03132800 on

  • IAW
    Participant
     IAW on

    The simple fact is that when Vitamin D stores are low (25-Hydroxy levels), then 1.25 D goes “high”.
    The Vitamin D Council exists because even though the lab range starts at 30 ng/ml, it is not a healthy level for a human to have. Numerous studies and reasoning points to higher levels. We promote 50 ng/ml or above. So you are below our threshold.
    You should try and raise your Vitamin D levels up to 50ng/ml. No there is nothing unusual, environmental or genetic going on.

    Answered by  IAW on
  •  vivavintageapparel03132800 on

    I tried supplementing with D3, but when my 25-OH-D levels went up, my 1,25 D levels went even higher, to 170. Now my endo is worried about me supplementing with vitamin D. Could there be any other causes for this to be happening?

    Answered by  vivavintageapparel03132800 on

  • IAW
    Participant
     IAW on

    I do not know if this will help. http://www.aafp.org/afp/recommendations/viewRecommendation.htm?recommendationId=140
    Why is your 1.25 being measured?

    Answered by  IAW on

Recent Discussion

Popular Questions