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For many years had severe vitamin D deficiency (under 10 ng). I experienced no health issues. Yet when doc recommended that I take D (as I don't go outdoors). Nothing he gave me, worked. Nothing. D drops 2000 IU/day, then injection (300K IU). Nothing would raise my D level. Yet after being prescribed Bio-Tech 50,000 IU/once a week. After only 6 months, my D level went up to 50-55 ng. I then continued the weekly 50K/week for over a year. Though D remained at that exceptionally high level for me (no more than 60 ng). My vitamin A went down for first time ever to 45 mcg/dl (all my life been tested for A, and was always from 90-100 mcg/dl). Also elements like Fe, Cu, and Cp (ceruloplasmin) sank into the bottom of lab range! Now I have skin issues (rash, dermatitis), falling, dry, brittle hair. Constipation (thou Ca level same, not high). Don't know what gone wrong! Even my doctor has no idea why or what cause of my problem. Thou he thinks, its possible the extra vitamin D, caused a reduction in vitamin A level. Other than that, we both puzzled as to why my state of health deteriorated. I've taken Cu 5 mg daily. Also eat many foods high in Cu, such as cashews, sesame, almonds. Estimate total daily consumption Cu 7-8 mg. Yet all lab readings of Cu, Cp, Fe, Ferritin fall in , bottom end of range. * Vitamin C 500 mg, was stopped, as it was suspected to be cause of Cu, Cp depletion. I'm thinking of completely stopping D. Taking mega dose vitamin A (retinol), as I done some research, where some good health sources recommend adding vit A, to correct low Cp levels. Will have to experiment on self, retest and see. Any helpful thoughts, ideas! Thank you.

Asked by  CARLMAN on May 6, 2017

Answers
  •  CARLMAN on

    See title

    Answered by  CARLMAN on
  •  IAW on

    First, 2000iu is not enough to raise levels. Most people need 5000iu a day to get to 50ng/ml. Taking really large doses or injections, once a month, studies are finding, does more harm than good. Taking Vitamin D once a week is OK but it is better to take smaller amounts daily. The 50,000iu once a week equals about 7000iu a day and gets you to the level we recommend.
    I try to emphasize to everyone that they read https://www.vitamindcouncil.org/about-vitamin-d/vitamin-d-and-other-vitamins-and-minerals/. It is very important! It lists the following as co-factors for Vitamin D: Magnesium, Vitamin K, Zinc, Boron and Vitamin A. So yes Vitamin D can “deplete” these because it needs these co-factors so it can do its job.
    You said “Now I have skin issues (rash, dermatitis), falling, dry, brittle hair and constipation.” (Did you mean your hair is falling out or that you fall down?) Are these all of your symptoms? I am not a doctor but since Vitamin D can deplete things maybe perhaps it is actually zinc that is depleted according to some of your symptoms. Also low magnesium can cause constipation. Do you take any supplemental magnesium? Vitamin D uses a lot of magnesium. I cannot stress this enough.
    I would be careful how much retinol you take because Dr. Cannel once warned us that too much may not be good and recommends not going over the daily RDA.
    Instead of completely stopping the D here is another suggestion. Take the Vitamin D daily and take 5000iu a day. (I’ll be honest, I really do not know if this will help or be of any benefit.) Then maybe consider which vitamin and/or mineral you “might” have a deficient in. This could take some trial and error.
    Those symptoms can also fall into a thyroid problem (hypothyroidism) that may not have had anything to do with the Vitamin D and was a coincidence. If this was the case I would think you would also be tired.
    Although we promote maintaining a healthy Vitamin D level of a minimum of 50ng/ml, keeping it above 40ng/ml would be good. There is too much research that shows at levels below 40ng/ml and your chances for cancer and autoimmune disease rises “dramatically”. In other words if you take the 5000iu and have 40ng/ml or better and your symptoms improve, then maybe you should stick with that.

    Answered by  IAW on
  •  CARLMAN on

    Thanks IAW. I was referring to falling hair, patchy hair loss (top of head). Think it is related to low Fe, Cu levels. You’re correct about not overdosing on preformed A. I will take one 10,000 i.u of Solgar vitamin A caps/day, and see if any change/improve/worsening of skin condition. As far as Mg. Level is good (mid range), as it’s always been.

    Answered by  CARLMAN on
  •  IAW on

    What many people do not know when it comes to blood mineral levels, is that they only measure the 1-2 percent that is found in your bloodstream and NOT your “total body stores”.So “no” the level does not prove that you actually have enough to accomplish body processes. You may still have a deficit.

    Answered by  IAW on

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