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Study underway to look at role of vitamin D in improving mood, reducing blood pressure in type 2 diabetes

Posted on: February 27, 2014   by  Vitamin D Council


Researchers out of Loyola University in Chicago are recruiting people for their trial to determine if vitamin D can improve mood and lower blood pressure in women with type 2 diabetes.

Type 2 diabetes (T2D) is often associated with mood related disorders such as depression. Additionally, those with T2D often have markers of increased cardiovascular risk such as high insulin resistance and increased blood pressure. Just this past December, a different research team from the same university published a study showing that vitamin D reduced depression and pain in women with T2D.

Vitamin D deficiency is common in those with T2D. Vitamin D deficiency has also been associated with depression and increased blood pressure.

So researchers, funded by a grant from the National Institutes of Health, are launching a study to see if vitamin D supplementation may have direct benefits on mood and blood pressure in those with T2D.

The team of researchers are currently recruiting women between the age of 21 and 75 who have T2D, low levels of vitamin D, are overweight and report symptoms of depression.

The women will be randomly assigned to receive either 50,000 IU/week of vitamin D3 or 5,000 IU/week. The women will be on this treatment until the trial is completed in 2017.

“Using a higher dose of vitamin D is potentially an easy and cost-effective way to improve mood,” said lead researcher Dr. Sue Penckofer. “Improving mood may make these women more likely to eat properly, take their medication, get enough exercise and better manage their disease overall.”

For more information on the study and to see if you are eligible to participate, call (708) 216-9303.


Dudley, N. Loyola Study to Determine if Vitamin D Supplements will Improve Mood in Women with Type 2 Diabetes. Chicago Tribune, 2014.

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