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Vitamin D Research

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Toxin and Radiation Exposure

A combined pretreatment of 1,25-dihydroxyvitamin D3 and sodium valproate enhances the damaging effect of ionizing radiation on prostate cancer cells. J Steroid Biochem Mol Biol. 2010 Mar 7.
The impact of methylmercury on 1,25-dihydroxyvitamin D3-induced transcriptomic responses in dolphin skin cells. Biol Chem. 2009 Dec 23.
Bladder cancer incidence and mortality rates compared to ecologic factors among states in America. Int Urol Nephrol. 2009 Oct 7.
Understanding and Determining the Etiology of Autism. Cell Mol Neurobiol. 2009 Sep 23.
Environmental risk factors for autism: Do they help cause de novo genetic mutations that contribute to the disorder? Med Hypotheses. 2009 Aug 20.
FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study. J Clin Endocrinol Metab. 2009 Jul;94(7):2332–7.
Osteopenia in Alcoholics: Effect of Alcohol Abstinence. Alcohol Alcohol. 2009 Jun 17.
The role of cigarette smoking and statins in the development of postmenopausal osteoporosis: a pilot study utilizing the Marshfield Clinic Personalized Medicine Cohort. Osteoporos Int. 2009 Jun 9.
Effects of 3,3',4,4',5-pentachlorobiphenyl (PCB126) on vertebral bone mineralization and on thyroxin and vitamin D levels in Sprague-Dawley rats. Toxicol Lett. 2009 Jun 1;187(2):63–8.
SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis. Am J Pathol. 2009 Jun;174(6):2324–36.
Urine proteomic profiling of uranium nephrotoxicity. Biochim Biophys Acta. 2009 Jun;1794(6):882–91.
Dioxin-induced up-regulation of the active form of vitamin D is the main cause for its inhibitory action on osteoblast activities, leading to developmental bone toxicity. Toxicol Appl Pharmacol. 2009 May 1;236(3):301–9.
Drug-induced hypersensitivity syndrome: clinical and biologic disease patterns in 24 patients. Medicine (Baltimore). 2009 May;88(3):131–40.
The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. Toxicol Sci. 2009 May;109(1):50–8.
Bile Acid sulfation: a pathway of bile acid elimination and detoxification. Toxicol Sci. 2009 Apr;108(2):225–46. Review.
Vitamin D metabolism impairment in the rat's offspring following maternal exposure to 137cesium. Arch Toxicol. 2009 Apr;83(4):357–62.
The combination of vitamin D(3) and dehydroascorbic acid administration attenuates brain damage in focal ischemia. Neurol Sci. 2009 Mar 6.
Effect of gestational ethanol exposure on parvalbumin and calretinin expressing hippocampal neurons in a chick model of fetal alcohol syndrome. Alcohol. 2009 Mar;43(2):147–61.
Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia. Leukemia. 2009 Mar;23(3):545–56.
Angiotensin-converting enzyme inhibitory and antioxidant activities of enzymatically synthesized phenolic and vitamin glycosides. Biotechnol Appl Biochem. 2009 Mar;52(Pt 3):177–84.
Macro- and micronutrient dyshomeostasis in the adverse structural remodelling of myocardium. Cardiovasc Res. 2009 Feb 15;81(3):500–8. Review.
CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides. Toxicol Lett. 2009 Feb 10;184(3):159–68.
Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells. Toxicol Appl Pharmacol. 2009 Feb 1;234(3):345–60.
Mechanisms of estrogen-induced effects in avian reproduction caused by transovarian application of a xenoestrogen, diethylstilbestrol. Arch Toxicol. 2009 Feb;83(2):161–71.
Cadmium-induced bone effect is not mediated via low serum 1,25-dihydroxy vitamin D. Environ Res. 2009 Feb;109(2):188–92.
Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post–)transcriptional modulators? Clin Rev Allergy Immunol. 2009 Feb;36(1):52–61. Review.
Some new food for thought: the role of vitamin D in the mental health of older adults. Curr Psychiatry Rep. 2009 Feb;11(1):12–9.
Uranium: properties and biological effects after internal contamination. Ann Biol Clin (Paris). 2009 Jan–Feb;67(1):23–38. Review.
Nuclear receptors as therapeutic targets in cholestatic liver diseases. Br J Pharmacol. 2009 Jan;156(1):7–27. Review.
25-Hydroxyvitamin D(3) is a natural chemopreventive agent against carcinogen induced precancerous lesions in mouse mammary gland organ culture. Breast Cancer Res Treat. 2009 Jan;113(1):31–41.
Severe Vitamin D-deficiency and the Health of North China Children. Matern Child Health J. 2009 Jan;13(1):144–50.
Differential alterations in the relations among GABAergic, catecholaminergic and calcium binding protein expression in the olfactory bulb of amphetamine-administered mouse. Neurotoxicology. 2009 Jan;30(1):103–13.
Vitamin D and neurocognitive dysfunction: preventing "D"ecline? Mol Aspects Med. 2008 Dec;29(6):415–22. Review.
Tackling critical issues for breastfeeding: vitamin D and environmental toxins. Breastfeed Med. 2008 Dec;3(4):205.
PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics. Pharmacogenomics. 2008 Nov;9(11):1695–709. Review.
Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. Nutr Rev. 2008 Oct;66(10 Suppl 2):S98–112. Review.
Nutritional calcium modulates colonic expression of vitamin D receptor and pregnane X receptor target genes. Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S45–51.
Enriched uranium affects the expression of vitamin D receptor and retinoid X receptor in rat kidney. J Steroid Biochem Mol Biol. 2008 Jun;110(3–5):263–8.
Vitamin D deficiency, cardiac iron and cardiac function in thalassaemia major. Br J Haematol. 2008 Jun;141(6):891–4.
Lithocholic acid can carry out in vivo functions of vitamin D. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10006–9.
Elevated blood lead concentrations and vitamin D deficiency in winter and summer in young urban children. Environ Health Perspect. 2007 Apr;115(4):630–5.
Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol. 2007 Mar 30;8:5.
An ecologic study of cancer mortality rates in Spain with respect to indices of solar UVB irradiance and smoking. Int J Cancer. 2007 Mar 1;120(5):1123–8.
In vivo effects of chronic contamination with depleted uranium on vitamin D(3) metabolism in rat. Biochim Biophys Acta. 2007 Feb;1770(2):266–72.
Xenobiotic- and vitamin D-responsive induction of the steroid/bile acid-sulfotransferase Sult2A1 in young and old mice: the role of a gene enhancer in the liver chromatin. Gene. 2007 Jan 15;386(1–2):218–23.
1,25-Dihydroxyvitamin D(3) regulates genes responsible for detoxification in intestine. Toxicol Appl Pharmacol. 2007 Jan 1;218(1):37–44.
Fluorotoxic metabolic bone disease: an osteo-renal syndrome caused by excess fluoride ingestion in the tropics. Bone. 2006 Oct;39(4):907–14.
The effects of air pollution on the health of children. Paediatr Child Health. 2006 Oct;11(8):513–6.
Chronic contamination with 137Cesium affects Vitamin D3 metabolism in rats. Toxicology. 2006 Aug 1;225(1):75–80.
Effects of depleted uranium after short-term exposure on vitamin D metabolism in rat. Arch Toxicol. 2006 Aug;80(8):473–480.
Recent studies on vitamin D metabolizing enzymes. Clin Calcium. 2006 Jul;16(7):1129–35. Review.
Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations. Mol Pharm. 2006 May–Jun;3(3):231–51. Review.
Coordinate regulation of hepatic bile acid oxidation and conjugation by nuclear receptors. Mol Pharm. 2006 May–Jun;3(3):212–22. Review.
Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr Drug Metab. 2006 May;7(4):349–65. Review.
Short-term hepatic effects of depleted uranium on xenobiotic and bile acid metabolizing cytochrome P450 enzymes in the rat. Arch Toxicol. 2006 Apr;80(4):187–95.
The preventive effect of vitamin D3 on radiation-induced hair toxicity in a rat model. Life Sci. 2006 Feb 28;78(14):1646–51.
Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). Nucl Recept. 2005 Sep 30;3:2.
C. elegans DAF-12, Nuclear Hormone Receptors and human longevity and disease at old age. Ageing Res Rev. 2005 Aug;4(3):351–71. Review.
Regulation of sulfotransferases by xenobiotic receptors. Curr Drug Metab. 2005 Aug;6(4):299–307. Review.
Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4. J Cell Biochem. 2005 Apr 1;94(5):917–43.
Vitamin D receptor regulation of the steroid/bile acid sulfotransferase SULT2A1. Methods Enzymol. 2005;400:165–91. Review.
Cross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences. Xenobiotica. 2004 Jul;34(7):633–64. Review.
Patterns of selective neuronal damage in methamphetamine-user AIDS patients. J Acquir Immune Defic Syndr. 2003 Dec 15;34(5):467–74.
Cloning of a functional vitamin D receptor from the lamprey (Petromyzon marinus), an ancient vertebrate lacking a calcified skeleton and teeth. Endocrinology. 2003 Jun;144(6):2704–16.
The role of the enterohepatic circulation of bile salts and nuclear hormone receptors in the regulation of cholesterol homeostasis: Bile salts as ligands for nuclear hormone receptors. Can J Gastroenterol. 2003 Apr;17(4):265–71. Review.
Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements. Biochem Biophys Res Commun. 2002 Dec 20;299(5):730–8.
Expression profiling confirms the role of endocytic receptor megalin in renal vitamin D3 metabolism. Kidney Int. 2002 Nov;62(5):1672–81.
Molecular biology of deregulated gene expression in transformed C3H/10T1/2 mouse embryo cell lines induced by specific insoluble carcinogenic nickel compounds. Environ Health Perspect. 2002 Oct;110 Suppl 5:845–50.
Season modifies the relationship between bone and blood lead levels: the Normative Aging Study. Arch Environ Health. 2002 Sep–Oct;57(5):466–72.
Few smokers develop COPD. Why? Respir Med. 2002 Aug;96(8):615–24. Review.
New clues about vitamin D functions in the nervous system. Trends Endocrinol Metab. 2002 Apr;13(3):100–5. Review.
Transcriptional regulation of the sodium-sulfate cotransporter NaS(i)-1 gene. Cell Biochem Biophys. 2002;36(2–3):175–82. Review.
The delta-aminolevulinic acid dehydratase (ALAD) polymorphism and bone and blood lead levels in community-exposed men: the Normative Aging Study. Environ Health Perspect. 2001 Aug;109(8):827–32.
Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats. Brain Res. 2001 Jun 15;904(1):67–75.
The influence of smoking on vitamin D status and calcium metabolism. Eur J Clin Nutr. 1999 Dec;53(12):920–6.
Genetic risk factors for chronic obstructive pulmonary disease (COPD). Nippon Rinsho. 1999 Sep;57(9):1954–8. Review.
1,25-dihydroxyvitamin D3 regulates the synthesis of gamma-glutamyl transpeptidase and glutathione levels in rat primary astrocytes. J Neurochem. 1999 Aug;73(2):859–66.
Mortality in a cohort of licensed pesticide applicators in Florida. Occup Environ Med. 1999 Jan;56(1):14–21.
Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. FASEB J. 1998 Oct;12(13):1409–17.
Measurement of vitamin D3 metabolites in smelter workers exposed to lead and cadmium. Occup Environ Med. 1998 Jul;55(7):446–52.
Vitamin D binding protein variants and the risk of COPD. Am J Respir Crit Care Med. 1998 Mar;157(3 Pt 1):957–61.
Clinical manifestation, diagnosis and treatment of rare forms of acute drug poisoning (lecture). Ter Arkh. 1998;70(10):65–8.
Influence of the vitamin D status on the early hepatic response to carcinogen exposure in rats. J Pharmacol Exp Ther. 1997 Apr;281(1):464–9.
1,25-Dihydroxyvitamin D3 regulates gamma 1 transpeptidase activity in rat brain. Neurosci Lett. 1996 Oct 4;216(3):183–6.
Acute drug poisonings. Eksp Klin Farmakol. 1995 Mar–Apr;58(2):11–6.
Studies on health effects of cadmium exposure in the general environment. Nippon Eiseigaku Zasshi. 1995 Feb;49(6):960–72.
Human monocyte chemotaxis to complement-derived chemotaxins is enhanced by Gc-globulin. J Leukoc Biol. 1994 Mar;55(3):349–54.
Vitamin D and aluminum absorption. CMAJ. 1992 Nov 1;147(9):1308, 1313.
Gcglobulin functions as a cochemotaxin in the lower respiratory tract. A potential mechanism for lung neutrophil recruitment in cigarette smokers. Am Rev Respir Dis. 1991 Apr;143(4 Pt 1):844–9.
Inactivation of chemotactic factor inactivator by cigarette smoke. A potential mechanism of modulating neutrophil recruitment to the lung. Am Rev Respir Dis. 1990 Oct;142(4):763–8.
Aluminum toxicity. Klin Wochenschr. 1989 Dec 15;67(24):1221–8. Review.
Acid haze air pollution and breast and colon cancer mortality in 20 Canadian cities. Can J Public Health. 1989 Mar–Apr;80(2):96–100.
Mediation of cellular anion detoxification in leukemic cells by unidirectional efflux pumps. Adv Enzyme Regul. 1989;29:61–72.
Aluminum:related bone disease. Blood Purif. 1988;6(1):1–15.
The effect of anti-tuberculosis chemotherapy on vitamin D and calcium metabolism. Tubercle. 1987 Dec;68(4):261–6.
Influence of cadmium on the metabolism of vitamin D3 in rats. Toxicol Appl Pharmacol. 1987 Jun 30;89(2):158–64.
Effects of elevated lead and cadmium burdens on renal function and calcium metabolism. Arch Environ Health. 1986 Mar–Apr;41(2):69–76.
Vitamin D 3 metabolism during anti-tuberculosis chemotherapy. Tubercle. 1985 Jun;66(2):151–2.
Metabolic mechanisms of drug-nutrient interactions. Fed Proc. 1985 Jan;44(1 Pt 1):124–9. Review.
19-nor-10-ketovitamin D derivatives: unique metabolites of vitamin D3, vitamin D2, and 25-hydroxyvitamin D3. Biochemistry. 1983 Jul 19;22(15):3636–40.
Accumulation of aluminum in a nondialyzed uremic child receiving aluminum hydroxide. Pediatrics. 1983 Jan;71(1):56–8.
Renal tubular dysfunction and abnormalities of calcium metabolism in cadmium workers. Environ Health Perspect. 1979 Feb;28:155–9.
Enzyme induction by drugs. Its relevance to clinical biochemistry. Ann Clin Biochem. 1978 Jan;15(1):55–64. Review.
Interrelationships of mycotoxins with nutrition. Fed Proc. 1977 May;36(6):1899–902. Review.
New knowledge about vitamin D and fluorides. Zahnarztl Mitt. 1976 Jun 1;66(11):546–50.
Subcortical tonic epilepsy type of seizure, with intracerebral calcareous deposits and parathyroid insufficiency suppressed by calciferol; physiopathological nosological and etiological discussion: possible role of carbon monoxide poisoning. Ann Med Interne (Paris). 1954;55(4):321–59.

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