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Vitamin D Research

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Cancer

Vitamin D: Proteases, protease inhibitors and cancer. Cell Cycle. 2010 Jan 5;9(1).
The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control. Biochem Pharmacol. 2010 Jan 1;79(1):1–9. Review.
Possible Health Implications and Low Vitamin D Status during Childhood and Adolescence: An Updated Mini Review. Int J Endocrinol. 2010;2010:472173.
20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes. J Cell Physiol. 2009 Dec 17.
Vitamin D in health and disease: an insight into traditional functions and new roles for the 'sunshine vitamin'. Nutr Res Rev. 2009 Dec;22(2):118–36.
Epidemiology of vitamin D in health and disease. Nutr Res Rev. 2009 Dec;22(2):188–203.
Vitamin D: an evidence-based review. J Am Board Fam Med. 2009 Nov–Dec;22(6):698–706.
1{alpha},25-Dihydroxyvitamin D3 and Its TX527 Analog Inhibit the Growth of Endothelial Cells Transformed by Kaposi Sarcoma-Associated Herpes Virus G Protein-Coupled Receptor in Vitro and in Vivo. Endocrinology. 2009 Nov 13.
Conference Report: Seventh Annual AACR International Conference on Frontiers in Cancer Prevention Research. Cancer Prev Res (Phila Pa). 2009 Nov;2(11):995–8.
Growth/differentiation factor-15 inhibits differentiation into osteoclasts—a novel factor involved in control of osteoclast differentiation. Differentiation. 2009 Nov;78(4):213–22.
Potentially beneficial effects of climate changes. Ugeskr Laeger. 2009 Oct 26;171(44):3197–200.
Human CYP24 catalyzing the inactivation of calcitriol is post-transcriptionally regulated by miR-125b. Mol Pharmacol. 2009 Oct;76(4):702–9.
Glycosylation status of vitamin D binding protein in cancer patients. Protein Sci. 2009 Oct;18(10):2036–42.
p73 is essential for vitamin D-mediated osteoblastic differentiation. Cell Death Differ. 2009 Sep 25.
MicroRNA regulates human vitamin D receptor. Int J Cancer. 2009 Sep 15;125(6):1328–33.
Vitamin D receptor modulates the neoplastic phenotype through antagonistic growth regulatory signals. Mol Carcinog. 2009 Aug;48(8):758–72.
Glycosylation status of vitamin D binding protein in cancer patients. Protein Sci. 2009 Jul 29.
Comparing methods for accounting for seasonal variability in a biomarker when only a single sample is available: insights from simulations based on serum 25-hydroxyvitamin d. Am J Epidemiol. 2009 Jul 1;170(1):88–94.
Vitamin D for cancer prevention: global perspective. Ann Epidemiol. 2009 Jul;19(7):468–83.
Vitamin D and cancer mini-symposium: the risk of additional vitamin D. Ann Epidemiol. 2009 Jul;19(7):441–5.
Symposium in print on the epidemiology of vitamin D and cancer. Ann Epidemiol. 2009 Jul;19(7):439–40.
Ecological Studies Of Ultraviolet B, Vitamin D And Cancer Since 2000. Ann Epidemiol. 2009 Jul;19(7):446–54.
Is replacement therapy with nutritional and active forms of vitamin D required in chronic kidney disease mineral and bone disorder? Curr Opin Nephrol Hypertens. 2009 Jul;18(4):308–14.
Ganglioneuroblastoma-associated vitamin D deficiency rickets. J Pediatr Hematol Oncol. 2009 Jul;31(7):502–4.
SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis. Am J Pathol. 2009 Jun;174(6):2324–36.
Dietary vitamin D and cancers of the oral cavity and esophagus. Ann Oncol. 2009 Jun 1.
Skeletal sequelae of cancer and cancer treatment. J Cancer Surviv. 2009 Jun;3(2):75–88.
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J Biol Chem. 2009 May 29;284(22):14838–48.
Treatment of K562 cells with 1,25-dihydroxyvitamin D(3) induces distinct alterations in the expression of apoptosis-related genes BCL2, BAX, BCL(XL), and p21. Ann Hematol. 2009 May 28.
The beneficial role of vitamin D and its analogs in cancer treatment and prevention. Crit Rev Oncol Hematol. 2009 May 13.
Skeletal sequelae of cancer and cancer treatment. J Cancer Surviv. 2009 May 2.
Vitamin D in cancer patients: above all, do no harm. J Clin Oncol. 2009 May 1;27(13):2117–9.
Serum Proteomic Approach for the Identification of Serum Biomarkers Contributed by Oral Squamous Cell Carcinoma and Host Tissue Microenvironment (dagger). J Proteome Res. 2009 May 1;8(5):2173–2185.
Vitamin d. Int J Biochem Cell Biol. 2009 May;41(5):982–5.
Calcium plus vitamin D supplementation and mortality in postmenopausal women: the Women's Health Initiative calcium-vitamin D randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2009 May;64(5):559–67.
The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. Toxicol Sci. 2009 May;109(1):50–8.
Review and meta-analysis on Vitamin D Receptor polymorphisms and cancer risk. Carcinogenesis. 2009 Apr 29.
Serum proteomic profile of cutaneous malignant melanoma and relation to cancer progression: Association to tumor derived alpha-N-acetylgalactosaminidase activity. Cancer Lett. 2009 Apr 24.
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med. 2009 Apr 15;179(8):630–6.
Tonsillectomy may be an indicator of low vitamin D status, a risk factor for cancer later in life. Cancer Causes Control. 2009 Apr 2.
Symposium in Print on the Epidemiology of Vitamin D and Cancer. Ann Epidemiol. 2009 Apr 1.
Vitamin d deficiency masquerading as metastatic cancer: a case series. Am J Med Sci. 2009 Apr;337(4):245–7.
Genetic architecture of mouse skin inflammation and tumour susceptibility. Nature. 2009 Mar 26;458(7237):505–8.
Statins Do Not Affect Mineral Metabolism in Chronic Kidney Disease: A Retrospective Analysis. Nephron Clin Pract. 2009 Mar 14;111(4):c236–c239.
Latitude Variation in Pancreatic Cancer Mortality in Australia. Pancreas. 2009 Mar 6.
Estimated benefit of increased vitamin D status in reducing the economic burden of disease in Western Europe. Prog Biophys Mol Biol. 2009 Mar 3.
Oncogenic osteomalacia from pterygopalatine fossa mass. J Laryngol Otol. 2009 Mar 2:1–3.
Vitamin D metabolism and vitamin D traditional and nontraditional, target organs: implications for kidney patients. J Ren Care. 2009 Mar;35 Suppl 1:39–44.
Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells. Carcinogenesis. 2009 Mar;30(3):449–56.
Vitamin D: skeletal and extra skeletal effects; recommendations for good practice. Presse Med. 2009 Jan;38(1):43–54. Review.
Analysis of CYP27B1, Encoding 25-hydroxyvitamin D-1alpha-hydroxylase, as a Candidate Tumor Suppressor Gene in Primary and Severe Secondary/Tertiary Hyperparathyroidism. J Bone Miner Res. 2009 Jan;24(1):102–4.
Selective transcriptional regulation of aromatase gene by vitamin D, dexamethasone, and mifepristone in human glioma cells. Endocrine. 2008 Dec 31.
Vitamin D: current status and perspectives. Clin Chem Lab Med. 2008 Dec 22.
Does vitamin D make the world go 'round'? Mol Aspects Med. 2008 Dec;29(6):369–75. Review.
Gestational vitamin D deficiency: long-term effects on the brain. Nutr Rev. 2008 Dec;66(12):726–9. Review.
The vitamin D deficiency pandemic and consequences for nonskeletal health: Mechanisms of action. Mol Aspects Med. 2008 Dec;29(6):361–8. Review.
Assessment of vitamin D status and definition of a normal circulating range of 25-hydroxyvitamin D. Curr Opin Endocrinol Diabetes Obes. 2008 Dec;15(6):489–94. Review.
Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements. Fam Pract. 2008 Dec;25 Suppl 1:i44–9.
Update on vitamin D and evaluation of vitamin D status. Ann Endocrinol (Paris). 2008 Dec;69(6):501–10. In French.
Vitamin D analogs: Therapeutic applications and mechanisms for selectivity. Mol Aspects Med. 2008 Dec;29(6):433–52.
Novel Gemini vitamin D(3) analogs have potent antitumor activity. J Steroid Biochem Mol Biol. 2008 Nov;112(1–3):151–6.
Adequate level of vitamin D is essential for maintaining good health. Postepy Hig Med Dosw (Online). 2008 Oct 9;62:502–10. In Polish.
Inactivation of the Human Vitamin D Receptor by Caspase-3. Endocrinology. 2008 Oct 1.
Vitamin D, aging, and cancer. Nutr Rev. 2008 Oct;66(10 Suppl 2):S147–52. Review.
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev. 2008 Oct;29(6):726–76. Review.
Vitamin D and Sunlight: Strategies for Cancer Prevention and Other Health Benefits. Clin J Am Soc Nephrol. 2008 Sep;3(5):1548–54.
Vitamin D in health and disease. Clin J Am Soc Nephrol. 2008 Sep;3(5):1535–41.
Prospective study of combined treatment with interferon-alpha and active vitamin D3 for Japanese patients with metastatic renal cell carcinoma. Int J Urol. 2008 Sep;15(9):794–9.
25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med. 2008 Aug 11;168(15):1629–37.
Vitamin D and anti-aging medicine. Clin Calcium. 2008 Jul;18(7):980–5. Review in Japanese.
The noncalciotropic actions of vitamin D: recent clinical developments. Curr Opin Nephrol Hypertens. 2008 Jul;17(4):408–15. Review.
Vitamin D and living in northern latitudes—an endemic risk area for vitamin D deficiency. Int J Circumpolar Health. 2008 Jun;67(2–3):164–78. Review.
Prevalence & potential significance of vitamin D deficiency in Asian Indians. Indian J Med Res. 2008 Mar;127(3):229–38. Review.
Sun exposure and cancer survival in Norway: changes in the risk of death with season of diagnosis and latitude. Adv Exp Med Biol. 2008;624:43–54.
Vitamin D receptor agonists in the treatment of autoimmune diseases: selective targeting of myeloid but not plasmacytoid dendritic cells. J Bone Miner Res. 2007 Dec;22 Suppl 2:V69–73. Review.
Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med. 2007 Sep 10;167(16):1730–7. Review.
Prospective study of serum 25(OH)-vitamin D concentration and risk of oesophageal and gastric cancers. Br J Cancer. 2007 Jul 2;97(1):123–8.
Expanding role for vitamin D in chronic kidney disease: importance of blood 25-OH-D levels and extra-renal 1alpha-hydroxylase in the classical and nonclassical actions of 1alpha,25-dihydroxyvitamin D(3). Semin Dial. 2007 Jul;20(4):316–324.
Does solar exposure, as indicated by the non-melanoma skin cancers, protect from solid cancers: vitamin D as a possible explanation. Eur J Cancer. 2007 Jul;43(11):1701–12.
Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk. Prostate. 2007 Jun 15;67(9):911–23.
Vitamin d and its role in cancer and immunity: a prescription for sunlight. Nutr Clin Pract. 2007 Jun;22(3):305–22. Review.
Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Am J Clin Nutr. 2007 Jun;85(6):1586–91.
Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anticancer Drugs. 2007 Apr;18(4):447–57.
Phase I study of weekly DN-101, a new formulation of calcitriol, in patients with cancer. Cancer Chemother Pharmacol. 2007 Apr;59(5):581–7.
An ecologic study of cancer mortality rates in Spain with respect to indices of solar UVB irradiance and smoking. Int J Cancer. 2007 Mar 1;120(5):1123–8.
A meta-analysis of second cancers after a diagnosis of nonmelanoma skin cancer: Additional evidence that solar ultraviolet-B irradiance reduces the risk of internal cancers. J Steroid Biochem Mol Biol. 2007 Mar;103(3–5):668–74.
1,25-Dihydroxyvitamin D(3) regulates genes responsible for detoxification in intestine. Toxicol Appl Pharmacol. 2007 Jan 1;218(1):37–44.
The effect of combined treatment on head and neck human cancer cell lines with novel analogs of calcitriol and cytostatics.Oncol Res. 2007;16(11):517–25.
Mutational analysis of the vitamin D receptor does not support its candidacy as a tumor suppressor gene in parathyroid adenomas. J Clin Endocrinol Metab. 2006 Dec;91(12):5019–21.
Role of dihydroxyvitamin D(3) and its nuclear receptor in novel directed therapies for cancer. Gen Physiol Biophys. 2006 Dec;25 (4):339–53.
Solar ultraviolet-B exposure and cancer incidence and mortality in the United States, 1993–2002. BMC Cancer. 2006 Nov 10;6:264.
Epidemiology of disease risks in relation to vitamin D insufficiency. Prog Biophys Mol Biol. 2006 Sep;92(1):65–79. Review.
Vitamin D intake and the risk for pancreatic cancer in two cohort studies. Cancer Epidemiol Biomarkers Prev. 2006 Sep;15(9):1688–95.
Considering the potential benefits as well as adverse effects of sun exposure: Can all the potential benefits be provided by oral vitamin D supplementation? Prog Biophys Mol Biol. 2006 Sep;92(1):140–9. Review.
Vitamin D: its role in cancer prevention and treatment. Prog Biophys Mol Biol. 2006 Sep;92(1):49–59. Review.
Vitamin D physiology. Prog Biophys Mol Biol. 2006 Sep;92(1):4–8. Review.
Vitamin D deficiency: A global perspective. Arq Bras Endocrinol Metabol. 2006 Aug;50(4):640–6.
The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates. Anticancer Res. 2006 Jul–Aug;26(4A):2687–99.
The likely role of vitamin D from solar ultraviolet-B irradiance in increasing cancer survival. Anticancer Res. 2006 Jul–Aug;26(4A):2605–14.
Vitamin D and cancer. Anticancer Res. 2006 Jul–Aug;26(4A):2515–24. Review.
Cooperative antitumor effects of vitamin D(3) derivatives and rosemary preparations in a mouse model of myeloid leukemia. Int J Cancer. 2006 Jun 15;118(12):3012–21.
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst. 2006 Apr 5;98(7):451–9.
Vitamin D and African Americans. J Nutr. 2006 Apr;136(4):1126–9.
1,25-Dihydroxyvitamin D3 inhibits tumor necrosis factor-alpha-induced adhesion molecule expression in endothelial cells. Cell Biol Int. 2006 Apr;30(4):365–75.
The Molecular Basis of Vitamin D Receptor and beta-Catenin Crossregulation. Mol Cell. 2006 Mar 17;21(6):799–809.
Vitamin D analogs as anti-carcinogenic agents. Anticancer Agents Med Chem. 2006 Jan;6(1):53–71. Review.
The epidemiology of vitamin D and colorectal cancer: recent findings. Curr Opin Gastroenterol. 2006 Jan;22(1):24–9. Review.
Pharmacokinetics and tolerability of a single dose of DN-101, a new formulation of calcitriol, in patients with cancer. Clin Cancer Res. 2005 Nov 1;11(21):7794–9.
Vitamin D: important for prevention of osteoporosis, cardiovascular heart disease, type 1 diabetes, autoimmune diseases, and some cancers. South Med J. 2005 Oct;98(10):1024–7. Review.
Vitamin D3 treatment for locally advanced thyroid cancer: a case report. Endocr J. 2005 Oct;52(5):613–6.
Dietary recommendations to meet both endocrine and autocrine needs of Vitamin D. J Steroid Biochem Mol Biol. 2005 Oct;97(1–2):7–12. Review.
Inhibitory effect of 22-oxa-1,25-dihydroxyvitamin D3, maxacalcitol, on the proliferation of pancreatic cancer cell lines. J Steroid Biochem Mol Biol. 2005 Oct;97(1–2):173–7.
Vitamin D for health and in chronic kidney disease. Semin Dial. 2005 Jul–Aug;18(4):266–75. Review.
Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB. 2005 Jul;19(9):1067–77.
Benefits and requirements of vitamin D for optimal health: a review. Altern Med Rev. 2005 Jun;10(2):94–111. Review.
Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur J Clin Invest. 2005 May;35(5):290–304. Review.
Vitamin-D receptor (VDR) gene (Fok-I, Taq-I and Apa-I) polymorphisms in healthy individuals from north Indian population. Asian Pac J Cancer Prev. 2005 Apr–Jun;6(2):147–52.
The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control. 2005 Mar;16(2):83–95. Review.
Seasonal variation in the diagnosis of cutaneous melanoma and non-cutaneous malignancies: an Italian population-based study. Melanoma Res. 2005 Feb;15(1):69–72.
Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004 Dec;80(6 Suppl):1678S–88S. Review.
Genetics and biology of vitamin D receptor polymorphisms. Gene. 2004 Sep 1;338(2):143–56. Review.
Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191). Steroids. 2004 Sep;69(10):629–35.
1alpha,25-dihydroxyvitamin D3 inducible transcription factor and its role in the vitamin D action. Endocr Regul. 2004 Mar;38(1):29–38. Review.
Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004 Mar;79(3):362–71. Review.
Micronutrients and laryngeal cancer risk in Italy and Switzerland: a case-control study. Cancer Causes Control. 2003 Jun;14(5):477–84.
Characterization of human Gc protein-derived macrophage activation factor (GcMAF) and its functional role in macrophage tumoricidal activity. Adv Exp Med Biol. 2003;510:77–82.
Analysis of the vitamin D system in cervical carcinomas, breast cancer and ovarian cancer. Recent Results Cancer Res. 2003;164:239–46.
Ecologic studies of solar UVB radiation and cancer mortality rates. Recent Results Cancer Res. 2003;164:371–7. Review.
Pharmacokinetics of high-dose oral calcitriol: results from a phase 1 trial of calcitriol and paclitaxel. Clin Pharmacol Ther. 2002 Dec;72(6):648–59.
Vitamin D3 and vitamin D3 analogues as an adjunct to cancer chemo-therapy and radiotherapy. Curr Med Chem Anti-Canc Agents. 2002 Nov;2(6):683–90. Review.
Vitamin D and systemic cancer: is this relevant to malignant melanoma? Br J Dermatol. 2002 Aug;147(2):197–213. Review.
New clues about vitamin D functions in the nervous system. Trends Endocrinol Metab. 2002 Apr;13(3):100–5. Review.
An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation. Cancer. 2002 Mar 15;94(6):1867–75.
Vitamin D and vitamin D analogs in cancer treatment. Curr Drug Targets. 2002 Feb;3(1):85–94. Review.
Vitamin D and genomic stability. Mutat Res. 2001 Apr 18;475(1–2):69–87. Review.
Cancer chemoprevention using natural vitamin D and synthetic analogs. Annu Rev Pharmacol Toxicol. 2001;41:421–42. Review.
Vitamin D receptor polymorphisms are associated with altered prognosis in patients with malignant melanoma. Clin Cancer Res. 2000 Feb;6(2):498–504.
Vitamin D3 analogs and their 24-oxo metabolites equally inhibit clonal proliferation of a variety of cancer cells but have differing molecular effects. J Cell Biochem. 1997 Sep 1;66(3):413–25.
Treating tumor-bearing mice with vitamin D3 diminishes tumor-induced myelopoiesis and associated immunosuppression, and reduces tumor metastasis and recurrence. Cancer Immunol Immunother. 1995 Jul;41(1):37–45.
Suppression of in vivo growth of human cancer solid tumor xenografts by 1,25-dihydroxyvitamin D3. Cancer Res. 1987 Jan 1;47(1):21–5.
A survey of vitamin D deficiency in gastrointestinal and liver disorders. Q J Med. 1984 Winter;53(209):119–34.
Vitamin D metabolism and chronic liver disease. Ann Clin Lab Sci. 1984 May–Jun;14(3):189–97. Review.

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