Reply To: Hello, I am looking for an opinion on D3 supplementation for newborns. We have a 3-week-old daughter whose physician's assistant recommended we supplement with 4000 IU. I believe this was an accident — it seems to be an adult dose — but that is not the reason I'm writing.
It prompted me to look further into infant dosing recommendations, and what concerns me is the handful a handful of studies I found correlating early supplementation with an INcreased risk of allergies/atopy later in life. I put the citations below.
So my questions are about about the benefits vs. risks of supplementation. Are they two sides of the exact same coin? Or can you suggest a strategy that might provide one without the other? For example: delaying supplementation until a certain age, or keeping her blood levels within some intermediate range.
What would consider a minimum effective blood level to realize the important benefits?
Milner J D, Stein D M, McCarter R, Moon R Y. Early infant multivitamin supplementation is associated with increased risk for food allergy and asthma. Pediatrics 2004. 11427–32.32
Hypponen E, Sovio U, Wjst M, Patel S, Pekkanen J, Hartikainen A L. et al Infant vitamin D supplementation and allergic conditions in adulthood: northern Finland birth cohort 1966. Ann NY Acad Sci 2004. 103784–95.95
Bäck O, Blomquist HKS, Hernell O, Stenberg B. Does vitamin D intake during infancy promote the development of atopic allergy? Acta Derm Venereol. 2009;89(1):28–32. doi:10.2340/00015555-0541.
Wjst M. The vitamin D slant on allergy. Pediatr Allergy Immunol. 2006 Nov;17(7):477-83.