Reply To: I am hearing more and more about Vitamin D Binding Proteins. Specifically how proteins bind 100% when produced from the sun, but, do not bind completely when produced from supplements. How does this impact our body and is this the reasons why often there are some studies that show positive results from high levels of 25-OH-D (assuming form the sun), but, not from supplementation? I am trying to understand that dynamic better. Thanks and great job with this site.