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Pregnancy complications linked to D deficiency

Posted on: June 20, 2012   by  John Cannell, MD


A recent Spanish study conducted by Dr. Perez-Ferre under the supervision of Professor Alfonso Calle-Pascual of the Medicina Universidad Complutense in Madrid, Spain, studied the association between vitamin D levels in pregnant women and pregnancy complications.

Perez-Ferre N, Torrejon MJ, Fuentes M, Fernandez MD, Ramos A, Bordiu E, Del Valle L, Rubio MA, Bedia AR, Montañez C, Calle-Pascual AL.  Association of low serum 25-Hydroxyvitamin D levels in pregnancy with glucose homeostasis and obstetric and newborn outcomes. Endocr Pract. 2012 May 1:1-18.

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4 Responses to Pregnancy complications linked to D deficiency

  1. Jenbyers2003

    Wow! Having the chance to work on a Vit D and pregnancy study I cant wait to see the Drs finally tell their patients to take more D!

  2. [email protected]

    My niece was fortunate enough to have an obstetrician who tested vit D level at the first pre-natal appt, as my niece’s vit D level came back at 29 nmol/L, which could have caused rickets in her baby. Her obstetrician immediately recommended 4000 iu per day through out the pregnancy! I was very pleased and excited as it seems the vitamin D news is getting out in Australia and our Drs are taking note!!!

    • Brant Cebulla

      Annie, that’s impressive! We have heard stories of obstetricians worried about vitamin D supplementation because they are not aware of the Wagner/Hollis RCTs. They see how much higher it is than government recommendations (6-8 times recommendation of 600 IU/day!) and are worried about teratology without basis. This is somewhat understandable — it’s only natural to fear what you don’t know.

  3. [email protected]

    It is also natural to fear what you have been told to fear.
    For over 40 years doctors were told in med school that patients would turn to stone if they had more the 2,000 IU of vitamin D. That “instruction” was based on a single incorrect diagnosis in the 1950’s in one country.
    That fear/myth is still in the medical profession today.
    It is only during the last decade that it is no longer being taught/propagated.
    If were are to have to rely on doctors to come around to embracing instead of rejecting vitamin D we would have to wait until the 1955-1995 cohort of doctors retire.
    By the way –
    it took me several months of reading the literature to realize than > 2,000 IU of vitamin D was OK. After about a year of reading I became aware that 10,000 IU of vitamin D is fine. see the chart at http://www.vitamindwiki.com/tiki-index.php?page_id=898, I currently average 12,500 IU of vitamin D in the dark winter around Seattle. Did you know that of all 15 of the cloudiest cities in the US are in Western Washington? http://www.vitamindwiki.com/tiki-index.php?page_id=870

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