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Oral vitamin D boosts intranasal steroid in rhinitis

Posted on: March 12, 2012   by  Vitamin D Council

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Researchers found that oral vitamin D taken in combination with intranasal corticosteroids can improve symptoms associated with allergies when compared to corticosteroids alone, according to a study presented at the American Academy of Allergy, Asthma and Immunology 2012 Annual Meeting.

In the double-blind, placebo-controlled trial patients ages 18-45 with seasonal allergic rhinitis received fluticasone propionate 200 µg/day, and were randomly assigned to either a placebo group (n=18) or a 4,000IU/day vitamin D group (n=17) for two weeks.

At baseline, vitamin D levels were similar in both groups (29.6 vs. 29.4ng/mL). After supplementation, levels in the vitamin D group increased to 37.2 ng/mL with no rise in the placebo group.

Participants in both groups reported a decrease in sneezing, nasal congestion, and drip. However, subjects in the vitamin D group reported an average symptom score drop of 6.9 points from baseline, compared to just 3.7 in the placebo group.
The lead author of the study stated,

“Just giving vitamin D on top created a significant drop — almost a 50% drop. The magnitude is impressive, actually. If that is duplicated in a big trial, it would be pretty spectacular.”

Source:
Baroody F, et al. The Addition of Vitamin D (VitD) to an Intranasal Steroid (INS) Improves Control of Symptoms in Seasonal Allergic Rhinitis (SAR). The Journal of Allergy and Clinical Immunology. Feb 2012.

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