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Open-label pilot trial: Vitamin D helps manage Crohn’s

Posted on: May 11, 2013   by  Kate Saley


A new open label carried out by Professor Linlin Yang and colleagues reports that vitamin D may be of help to people with Crohn’s disease.

Crohn’s disease is an inflammatory bowel disease that affects the gastrointestinal tract. Symptoms are unpleasant, including abdominal pain, diarrhea, vomiting, or weight loss, so management of these symptoms is important. The incidence of inflammatory bowel disease in general has risen the past 50 years, making many believe their might be some environmental factor causing the increase. Past research has shown that people with Crohn’s are deficient in vitamin D, and since vitamin D plays a beneficial role in other auto-immune diseases by way of reducing inflammation and smartening the immune system, researchers want to know if vitamin D can help people with Crohn’s.

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1 Response to Open-label pilot trial: Vitamin D helps manage Crohn’s

  1. [email protected]

    Most likely would have had even more improvement if
    1) Had used the type of vitamin D which was designed for gut problems
    2) Had started with a loading dose
    3) Had the vitamin D levels >40 ng for more than just 2 months
    4) Had gone for more than vitamin D monotherapy: e.g. Magnesium and/or Vitamin K2
    details on study, along with suggestions and links to other gut studies is at

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