A new study in Europe is set to get underway examining the effect of vitamin D and lifestyle interventions on gestational diabetes.
Gestational diabetes is a condition in which pregnant women get high blood glucose, usually during their third trimester. What happens in gestational diabetes is that the pancreas can’t produce enough insulin to keep up with the body’s needs, coupled with the body having general resistance to insulin. Consequently, pregnant mothers then have too much glucose in their blood.
Gestational diabetes can lead to some complications. Women are more likely to get preeclampsia or have to get a Caesarean section. Women are more likely to get type II diabetes later in life. Babies are more likely to be born large, which can lead to delivery complications. Babies are also more likely to have childhood obesity.
In the new study underway, abbreviated DALI, researchers are enrolling 880 women to participate in a randomized controlled trial. The trial will have 8 different arms, with 110 women placed in each arm. The arms include:
The researchers will aim to see which arm prevents gestational diabetes the best.
DALI will be recruiting women from nine different countries, including United Kingdom, Ireland, Netherlands, Belgium, Poland, Italy, Spain, Austria, and Denmark. They hope to enroll women through December 2013 at the partnering centers in each country. The interventions will take place during the women’s third trimester.
To learn more, visit the DALI website: http://www.dali-project.eu/
Jelsma JGM et al. DALI: Vitamin D and lifestyle intervention for gestational diabetes mellitus (GDM) prevention: an European multicentre, randomised trial — study protocol. BMC Pregnancy Childbirth, 2013