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New study highlights specific role for vitamin D in prostate cell function

Posted on: September 12, 2014   by  Jeff Nicklas


In a new laboratory study published in PLoS One, researchers discovered a new way in which vitamin D helps maintain prostate cell functioning.

Cells in the body need to be able to communicate with each other to ensure proper functioning of various tissues. In order for cells to be able to do this, they need to connect together and form what is known as a gap junction.

A gap junction is the connection of the cytoplasm of two cells which allows them to transfer molecules and ions to each other, essentially allowing them to ‘communicate’. This is only possible with connexins, which are the proteins that form the gap junction between two cells.

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2 Responses to New study highlights specific role for vitamin D in prostate cell function

  1. PeterVermont

    Dr. Cedric Garland’s DINOMIT theory of cancer formation included loss of tight gap junctions as one of the steps. He wrote that vitamin D improved gap junctions partly through up regulation of cadherins which bind cells together.

  2. Tom Weishaar

    Since it has been shown that the vitamin D receptor in prostate cells responds to 25(OH)D, 1,25OH2D, and 24,25(OH)2D, producing, with some overlap, different proteins, it’s a puzzle why these researchers used activated vitamin D rather than 25(OH)D. In my mind the discovery that the vitamin D receptor responds to at least three versions of vitamin D was the most important vitamin D discover of 2013, yet no one seems to know about it! – Tom

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