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New study finds vitamin D status a predictor of mortality in people with HIV

Posted on: February 8, 2014   by  Vitamin D Council


Researchers have found that vitamin D deficiency is associated with increased risk of death among patients with HIV.

Vitamin D deficiency is common among people with HIV, and previous research has shown several relationships between vitamin D and HIV. For example, past research has suggested that getting enough vitamin D may help boost response to HIV treatment.

However, few studies have looked at vitamin D as a marker of mortality in those with HIV.

So researchers led by Dr. Leah Shepard of the University College London Medical School looked at 250 AIDS patients within the EuroSIDA cohort. EuroSIDA is a prospective observational cohort study of more than 9,700 patients followed in 72 hospitals in 26 European Countries. This was a case control study, so they matched these AIDS patients with 250 healthy controls also from the EuroSIDA cohort.

In this cohort, people got blood tests often. For these particular patients in this case-control study, the patients were followed for a median 44.6 months. They wanted to know if vitamin D was associated with risk of death.

What they found is that for every twofold increase in the latest vitamin D level drawn, there was a 46% reduced risk of dying. The median time between last blood draw and event of death was 3.1 months.

The researchers concluded, “Low vitamin D predicts short term mortality in HIV-positive persons.”

They recommended further study looking if vitamin D supplementation could help in HIV patients and reduce their mortality risk.


Shepherd, L. et al. Prognostic value of vitamin D level for all-cause mortality, and association with inflammatory markers, in HIV-infected persons. Journal of Infectious Diseases, 2014.

1 Response to New study finds vitamin D status a predictor of mortality in people with HIV

  1. Michael

    I met a man in San Francisco in 1968. He told me he was dying from a disease that had already killed all his friends and that the doctor had given him 6 months to live. What he described to me was later to be called AIDS. The experts, last time I heard, have tracked AIDS / HIV only back to the mid 70’s or so. This man and his friends were already dead from it ten years earlier. He lived on either Haight or else Ashbury and was a lawyer. He took me on a ride down the crookedest street in the world in a little red sports car and stopped at the door of a bar (it was daytime) where I could see into the dark depths from the car boys dancing in jock straps and G-strings.

    Long story short, gays were hit hard by HIV in great part by Vitamin D deficiency, Vitamin C deficiency, Vitamin A-Z deficiency, vegetable & fruit deficiency and too much booze.

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