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New study finds low vitamin D levels may relate to deep vein thrombosis

Posted on: July 2, 2014   by  Vitamin D Council


A recent study published in International Journal of General Medicine found that low vitamin D levels are associated with idiopathic deep vein thrombosis.

Deep vein thrombosis (DVT) is the formation of a blood clot in one or more deep veins. Idiopathic means that it is a condition that occurs unexpectedly or in which the cause is unknown.

DVT may develop if you are sitting for long periods of time or if you have certain medical conditions that affect your body’s ability to form blood clots.

Studies show that vitamin D may have anticoagulant properties, indicating that it may help prevent the clotting of blood.

Researchers in the current study hypothesized that vitamin D plays a role in DVT due to these properties.

They recruited 82 participants with idiopathic DVT and 85 healthy participants to serve as controls and compared the vitamin D levels between the two different groups.

They found that vitamin D levels were significantly lower in the participants with idiopathic DVT compared to the healthy participants.

The results showed that 68.3% of participants with DVT were vitamin D deficient, compared to 49.4% of the healthy participants.

“Low levels of vitamin D are associated with idiopathic lower-extremity DVT,” the researchers stated. “Further investigation is needed to establish determinants and probable causative role of vitamin D.”


Khademvatani,  K. et al. The relationship between vitamin D status and idiopathic lower-extremity deep vein thrombosis. International Journal of General Medicine, 2014.

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