New RCT provides clarity on vitamin D’s role in treating atopic dermatitis

Posted on: October 27, 2014   by  Amber Tovey

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A recent randomized controlled trial published in Journal of Allergy and Clinical Immunology found that vitamin D supplementation reduces the severity of atopic dermatitis.

Atopic dermatitis (AD) or eczema is a skin disorder characterized by itchy and inflamed patches of skin. Worldwide, up to twenty percent of children are affected by AD, and about one to three percent of adults are affected by AD.

Patients with AD are at an increased risk for skin infection. Itchy skin often causes the need to repeatedly scratch the skin, creating open sores and cracks.

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2 Responses to New RCT provides clarity on vitamin D’s role in treating atopic dermatitis

  1. Yasir Mahmood

    Thanks Ms Amber.
    Do you know any study of topical use of vitamin D along with some emollient to assess its effects in eczema and psoriasis? I read that Dr. Holick administer topical use of vitamin D in patients with psoriasis.

  2. Amber Tovey

    Hi Yasir,

    Vitamin D analogues are popular treatments for psoriasis.

    A common topical vitamin D analogue for psoriasis is calcipotriol. Here is a study from 2013 that compared the efficacy of calcipotriol to other popular treatments for psoriasis. It found the calcipotriol was the most successful.

    http://www.ncbi.nlm.nih.gov/pubmed/23986159

    Dr. Holick mentions calcipotriol as well as Galderma Laboratories’ Vectical (AKA calcitriol). Here is an open-label study that evaluated the safety and efficacy of topical calcitriol for psoriasis. They found that it was a safe and effective treatment.

    http://www.ncbi.nlm.nih.gov/pubmed/22106730

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