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New meta-analysis: Vitamin D supplementation of no concern in mild primary hyperparathyroidism

Posted on: January 9, 2014   by  Brant Cebulla


A new meta-analysis is out that says vitamin D supplementation is an okay measure to take in primary hyperparathyroidism.

Primary hyperparathyroidism (PHPT) is a condition where the parathyroid glands develop an adenoma, which is a non-cancerous tumor. This adenoma causes your parathyroid to produce too much parathyroid hormone, which can lead to a condition where you have too much calcium in your blood (hypercalcemia) and can compromise your bone health and cause osteoporosis.

Since vitamin D can increase your ability to absorb calcium in the gut, doctors are usually cautious to prescribe or recommend vitamin D, worried that it might tip your calcium balance a little too high.

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3 Responses to New meta-analysis: Vitamin D supplementation of no concern in mild primary hyperparathyroidism

  1. [email protected]

    A few people with Hyper-parathyroidism have had problems with larger amounts of Vitamin D, so caution is advised.

    If you have Hyper-parathyroidism:
    Maybe start with a blood test of your blood Vitamin D level to establish a baseline figure
    Then take 1,000 IU per day of Vitamin D3 for a week and watch for symptoms
    Then increase to 2,000 IU per day for the next week
    Then increase to 3,000 -> 4,000 IU or more in the following weeks
    Then re-test to find your resulting Vitamin D blood level
    ( 1,000IU = 25 micrograms / 4,000IU = 100 micrograms )

    Download the “Call-To-Action” from http://www.grassrootshealth.net
    This will better advise you and your doctor about your target blood levels
    ( 40-60 ng/mL in USA or 100-150 nmol/L in Europe & RoW )

    Some Thyroid problems may be related to Adrenal Fatigue, so these need to be sorted before you start taking Vitamin D

    I recently gave a talk about Vitamin D to a UK Thyroid support group
    You can see the presentation and listen to the talk at: http://www.vitamindwiki.com
    Search for Thyroid or: http://is.gd/thyroidrg

    Please download the talk and send me feedback about what has worked for you

    Rufus Greenbaum


    • Brant Cebulla


      I’m not familiar with any evidence that people with thyroid problems should use caution in taking vitamin D. Do you have any sources?

      People with parathyroid problems, on the other hand, need to consult their doctors before taking vitamin D, especially for the condition primary hyperparathyroidism, as explained in this blog.


  2. [email protected]

    This doesn’t deal with the cautions needed in taking vitamin D in people who have primary hyperparathyroidism.
    It offers a theory. That an important cause of primary hyperparathyroidism in some pepole which results in one or more adeonomas is decades of vitamin D deficiency which leads to stimulation of the parathyroids glands which have to work “overtime” to produce Parathyroid Hormone (to keep the vitamin d level at a safe level). The hyperplasia at some point becomes autonomous and develops into an adenoma. I’m not saying that vitamin D would cure it, but I am proposing the theory that prevention of vitamin D deficiency at an early age would prevent primary hyperparathyrordism in those that may be genetically susceptible.
    Robert Baker MD

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