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Meta-analysis: Vitamin D levels and risk of heart disease, early death

Posted on: September 18, 2012   by  John Cannell, MD


In 1981, Professor Robert Scragg first hypothesized that vitamin D deficiency contributed to heart disease. He used latitudinal, seasonal and altitudinal data to support his theory. Thirty-two years later, we are getting closer to understanding the truth of his theory.

Scragg R. Seasonality of cardiovascular disease mortality and the possible protective effect of ultra-violet radiation. Int J Epidemiol. 1981 Dec;10(4):337-41.

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2 Responses to Meta-analysis: Vitamin D levels and risk of heart disease, early death

  1. JBG

    “Then they did a metanalysis of 18 general population studies that included more than 82,000 people. The studies used various definitions of inadequacy. They found the risk of early death with “inadequate levels” was 46%.”

    46% of what? 46% of the 82,000 people died early??

  2. John Cannell, MD

    The people with the low levels had a 46% greater chance of death from heart disease.

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