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Low vitamin D levels related to symptom severity in first-episode schizophrenia

Posted on: March 25, 2014   by  Jeff Nicklas


New research published in Early Intervention in Psychiatry has found that vitamin D deficiency is associated with more severe symptoms and cognitive deficits in people with schizophrenia.

People with schizophrenia often have low vitamin D levels. This is because patients with schizophrenia are often hospitalized, or the nature of the disorder keeps them from getting proper sun exposure. While vitamin D deficiency is common in schizophrenia, there haven’t been any studies that have explored how low vitamin D levels might affect symptom severity.

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1 Response to Low vitamin D levels related to symptom severity in first-episode schizophrenia

  1. Rita and Misty

    While I agree that we need well designed randomized controlled trials to determine if vitamin D supplementation can improve symptom severity in those with schizophrenia, I also know just how long it takes to do such studies. We are talking 50 years or more….

    I think it is much better to immediately raise the patient’s 25(OH)D level to the higher end of optimal, with regular testing of calcium level for toxicity, and while monitoring for symptom improvement.

    It is the ratio of benefit versus harm. And benefit outweighs harm here, I think.

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