Research published in the journal PLOS ONE suggests that low vitamin D levels are associated with increased risk of developing statin induced myalgia.
Statin induced myalgia (SIM) refers to muscle pain due to taking statins. Around 10-15% of people taking statins experience myopathy (general muscle problems) and/or myalgia.
It’s not clear why taking statins affects some people’s muscles. One thought is that statins cause decreased levels of coenzyme Q10, and in consequence, this may cause myopathy.
Researchers in the past have looked at the vitamin D levels of patients with SIM and compared those with patients on statins without SIM, to see if vitamin D might be involved. The findings have been mixed, with some studies showing SIM patients having lower vitamin D levels and other studies showing no relationship.