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Low D may be linked to ovarian cancer death risk

Posted on: August 17, 2012   by  Vitamin D Council


Research published this month in Clinical Biochemistry found that women who are vitamin D deficient with ovarian cancer have an increased risk of death compared to those who are vitamin D sufficient.

Dr Małgorzata Walentowicz-Sadlecka conducted the study of 72 epithelial ovarian cancer patients ages 37-79 who underwent optimal cytoreductive surgery. The participants’ vitamin D levels were tested before surgery and compared to vitamin D serum levels of 65 non-obese healthy controls aged 35-65 years.

Participants with ovarian cancer had significantly lower vitamin D levels when compared to the healthy women, 12.5 ng/mL vs. 22.4 ng/mL.

Dr Walentowicz-Sadlecka divided the ovarian cancer participants into two subgroups and analyzed survival. He found that the 5-year survival rate was significantly higher among women with vitamin D levels greater than 10 ng/mL compared to women with vitamin D levels less than 10 ng/mL.

In 2008 21,204 American women were diagnosed with ovarian cancer while there were 14,362 deaths, according to the CDC.

The author concludes,

“Testing for 25(OH)D in the standard procedure could help to find ovarian cancer patients with worse prognosis, who would benefit of special attention and supplementation.”


Walentowicz-Sadlecka M. 25(OH)D3 in patients with ovarian cancer and its correlation with survival. Clinical Biochemistry. Aug 2012.

Center for Disease Control. Gynecologic Cancers. Ovarian Cancer. May 30 2012.

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