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Large Australian trial underway on vitamin D supplementation and health outcomes

Posted on: July 30, 2014   by  Vitamin D Council


Researchers out of Australia are currently recruiting for one of the largest randomized controlled trials on vitamin D and health outcomes, called the D-Health study.

They are hoping to enroll 25,000 Australians ages 60-79 years to determine if vitamin D supplementation affects the risk of developing diseases such as cancer and heart disease.

The participants will be randomly selected to receive either 60,000 IU of vitamin D or placebo monthly for up to five years.

The researchers will gather information from hospital records, national health databases, and Medicare records.

“We hope that this study, linking with Medicare records and cancer registries, will be able to provide some definitive answers and advice,” said Dr. Rachel Neale, principal investigator.

Dr. Neale hopes that this study will add more evidence to vitamin D’s role in various areas of health. Other studies by Dr. Neale include one which found that participants living in areas with high UV radiation exposure had a 30-40% percent reduced risk ovarian, pancreatic, and esophageal cancer compared to those living in areas with low UV radiation exposure.

The D-Health study will provide more insight on the relationship between vitamin D and various health conditions and diseases, including different forms of cancer, due to its large sample size and long duration.

If you live in Australia and are interested in taking part in the study, visit http://dhealth.qimrberghofer.edu.au/ or call 1300 735 920 for more information.


Macdonald, K. Sun offers help in cancer battle. The West Australian, 2014.

4 Responses to Large Australian trial underway on vitamin D supplementation and health outcomes

  1. [email protected]

    1) 60,000 IU once a month, is NOT as the same as 2,000 IU/day. The average affect on the body over the month will be about 1,000 IU/day, which is not very much.

    2) Several studies have determined that a person should not take vitamin D any less frequently than about 18 days. Infrequent vitamin D puts the body on a chemical roller coaster.

    3) This will not be a Random Controlled Trial after about 3 months. People getting the Vitamin D will feel noticeably better than those who are getting just the placebo. (For the week after taking the monthly capsule)

  2. [email protected]

    4) Noticed that this trial is for seniors.
    40% of seniors in a trial getting 1600 IU daily for a year go NO increased vitamin D blood level.
    Several actually decreased their vitamin D levels!
    Details of the trial are at: http://vitamindwiki.com/tiki-index.php?page_id=2618
    Seniors should get 60,000 IU weekly, not once every 4 weeks.

  3. Ian

    I must agree with Henry on this and wonder why these studies persist in poor dosing regimes. In addition, I believe that 60 years + is actually too late. The damage done by vitamin D deficiency from age 45 years can be substantial. But I suppose the study is better than no study or a very small study with all the variables correct.

  4. IAW

    I whole heartedly agree with Henry and Ian. I think you can still have change at 60 years + BUT I think chronic Vitamin D deficiency absolutely leads to the devastating diseases that we are seeing.

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