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Is it safe to take near-physiological doses of vitamin D while using anti-hypertensive medication?

Posted on: October 13, 2014   by  Amber Tovey


A new analysis of a randomized controlled trial found that taking vitamin D supplements with hydrochlorothiazide is safe and does not increase the risk of hypercalcemia.

Hydrochlorothiazide (HCTZ) is a common treatment for hypertension and fluid retention. HCTZ helps the kidneys get rid of excess water and salt in the body.

When giving drugs or medications, it is important that doctors and clinicians be aware of potential contraindications. A contraindication is when some factor in medical treatment interacts with or interferes with that medication providing enough reason to cease giving that treatment. An example of a contraindication is when a patient can’t undergo a certain procedure because it may cause more harm in relation to their medical condition.

There are certain contraindications in regards to vitamin D supplementation. There are certain medications and conditions in which it is not recommended to take high doses of vitamin D. Or vice versa, there are some medications that may mean a person will need to take more vitamin D than usual.

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5 Responses to Is it safe to take near-physiological doses of vitamin D while using anti-hypertensive medication?

  1. Rita and Misty

    I love the title of this blog “near-physiological doses of vitamin D….”

    Curiosity has me thinking of those folks taking near-pharmaceutical doses of vitamin D. Just understanding the nature of human beings has me certain that there are many folks taking these types of doses of D. It would be great to study these folks. In other words, it would be great to study folks who take near-pharmaceutical doses of vitamin D.

    Yes, I agree that it’s best to work in partnership with a physician knowledgeable and open to vitamin D. Where can we find those physicians? 😉 I’m at a loss.

  2. Yasir Mahmood

    Thanks to Ms Amber for another informative blog after a short while.

    Now awareness about vitamin D is growing stronger among scientist and physician. A recent study published in “AMERICAN JOURNAL OF CRITICAL CARE ” in 2014 entitled as “Deficiency in 25-hydroxyvitamin d and 30-day mortality in patients with severe sepsis and septic shock” unlocked new discipline to study vitamin D deficiency in broad spectrum than before.


  3. Magic


    We have talked about this before. There is NOTHING in it for the doctors. You take 28,000 all winter long but many doctors around Oregon and the same in New Haven cringe when more than 1000 is mentioned. TOXIC (the big bad word)has been so ingrained by the bad guys (big pharma). It is a shame. Doctors are overworked. Still they need patients to return on a regular basis.. We used to have refrigerators that would last way more than 30 years. Why do expensive refrigerators have a 8 to 13 year life expectancy? Repeat business.

    My coffee group of 8 guys with age ranging from 67 to 85 make me the standing joke. D3 giggle, giggle.

    Most are taking 1000-2000 now after my insisting that they just go to this site. None have gone.

  4. Rita and Misty

    Daily dose matters less than 25(OH)D level. Most folks reach optimal 25(OH)D level on 5,000 iu D3 daily. Some folks do not. That’s why it’s important to administer the 25(OH)D test. How else would you know what your vitamin D blood level is?

    The physicians I know are good people. They just aren’t up-to-speed on their vitamin D knowledge. Those physicians who are knowledgeable in vitamin D need to reach out to their colleagues.

    It is really just that simple. And that difficult.

  5. Rita and Misty

    The most successful magic available to us includes perseverance.

    In other words, steadfastness in doing something despite difficulty or delay in achieving success.

    AKA as stubbornness.
    Refusal to say “enough.”
    Inability to simply walk away.
    And, lack of concern regarding the opinions of others.

    Try visualizing yourself as a steamroller.


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