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Is curcumin mimicking vitamin D?

Posted on: June 19, 2013   by  John Cannell, MD

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There are relatively many studies on the health benefits of curcumin, a chemical compound in the spice turmeric, popularly found in curry spice blends and curry dishes. Some promising clinical trials have shown curcurmin is effective in various pro-inflammatory diseases, including cancer, cardiovascular disease, arthritis, Crohn’s disease, ulcerative colitis, irritable bowel disease, vitiligo, psoriasis, acute coronary syndrome, atherosclerosis, diabetes, diabetic nephropathy, lupus, and acquired immunodeficiency syndrome.

Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013 Jan;15(1):195-218. 

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9 Responses to Is curcumin mimicking vitamin D?

  1. D-fiant

    Maybe it was a devine thought or was it co-incidence, but as I was loading the VDC site I was thinking…… we all know here that Vit D helps in nearly everything the body does, so we don’t need anymore convincing (we love hearing about the research) but what we need now is – how do we supercharge the healing effect of Vit D.

    By that I mean, apart from co-factors, what can we do / add, with the building of our Vit D levels to get greater health and fight diseases. I did hear that our micro gut floria increases our Vit D levels, so that maybe one.

    Now; what about curcumin, is this another thing or in the future are we going to find that curcumin conflicts with Vit D?

  2. Rita and Misty

    @d-fiant,

    (of course this is only my opinion, however):

    If I had cancer, I would start a protocol of high d3, and goodly amounts of iodine and selenium.

  3. D-fiant

    Hi Rita,
    I got my Vit D level back last week, 198 (79.2) my highest level, going for about 250 (100). I had to prepare my doctor for such a high result, I did this by giving her a vit D report from VDC.

    I am still away from home, out boating and I got the results emailed to me. The doctor seemed to take the result in her stride as the secretary said the doctor said there was no action required. My son’s doctor, in the same practice (different doctor) had a fit when his hit about 170 (68)

    You know my story on pc.
    I have looked at selenium, but could not find a test that supported it conclusivly. Some tests saying high levels were bad for you.
    I have not looked at iodine, but I will now.

    Thanks for your continued support.

  4. Rita and Misty

    @de-fiant,

    If you are doing any fishing, may you have success…

    🙂

  5. Brant Cebulla

    D-fiant,

    You raise a good question about curcumin-vitamin D and if there are any contraindications. Unfortunately based on current research, we don’t know, so it’s hard to declare much of anything at the moment. I’m also not sure how much researchers are looking into this.

    Cheers,
    Brant

  6. Rita and Misty

    Hi di-fiant and Brant,

    Dr. Cannell’s closing line in his above article is excellent: “The benefits found in curcumin may work by curcumin masquerading as vitamin D.” That would be amazing..the power of such a masquerade leaves one’s head spinning, yes?… (BTW–Happy B-Day, Dr. Cannell) 🙂

    Brant, I did an extremely quick internet search on curcumin, and it appears to have very low toxicity, with some tremendous health benefits (plus it’s just a tasty spice-imo):

    Here are some fun, easy reads on the spice:

    http://nutritionwonderland.com/2009/08/turmeric-and-curcumin-show-major-health-benefits/
    http://www.nutraingredients.com/Research/Low-level-curcumin-supplements-have-diverse-health-effects

    For those of you with access to Pubmed Central, there many good scientific articles on curcumin.

    This below pubmed j.a. is excellent:

    Discovery of Curcumin, a Component of the Golden Spice, and Its Miraculous Biological Activities: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288651/

    Be well!

    Rita
    203-785-6269
    umileritac@aol.com

  7. mary-mccarthy@comcast.net

    Here is another interesting article about curcumin by microbiologist Dr. Gombart (from Oregon State University Linus Pauling Institute) and colleagues; “Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway.”

    http://oregonstate.edu/ua/ncs/archives/2012/may/curry-new-biological-role-identified-compound-used-ancient-medicine

    http://www.ncbi.nlm.nih.gov/pubmed/22841393

  8. Dan

    Note that Curcumin can deplete iron, same for Quercetin. I am recovering from low iron and had to stop these.

  9. allometric24

    I shall have to eat curried onions for lunch. I have been trying to lower my iron for a long time but they won’t take my blood round here!

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