A recent double-blind, single-centered randomized pilot study found high-dose vitamin D supplementation may help reduce the immune system’s hyperactivity in patients with multiple sclerosis (MS).
A total of 40 MS patients were included in the study. The patients were divided into two groups: group 1 received 10,400 IU of vitamin D3 daily and group 2 received 800 IU daily. The patient’s disease activity was evaluated at baseline, 3 months and 6 months.
The researchers found that high dose vitamin D supplementation was not only safe, but also effective in reducing the proportion of a specific type of immune system cell that is involved in the MS disease process.