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High-dose vitamin D supplementation may help treat multiple sclerosis

Posted on: January 3, 2016   by  Vitamin D Council


A recent double-blind, single-centered randomized pilot study found high-dose vitamin D supplementation may help reduce the immune system’s hyperactivity in patients with multiple sclerosis (MS).

A total of 40 MS patients were included in the study. The patients were divided into two groups: group 1 received 10,400 IU of vitamin D3 daily and group 2 received 800 IU daily. The patient’s disease activity was evaluated at baseline, 3 months and 6 months.

The researchers found that high dose vitamin D supplementation was not only safe, but also effective in reducing the proportion of a specific type of immune system cell that is involved in the MS disease process.


Sotirchos, E. et al. Safety and immunologic effects of high vs low dose cholecalciferol in multiple sclerosis. Neurology, Dec. 2015. 

3 Responses to High-dose vitamin D supplementation may help treat multiple sclerosis

  1. [email protected]

    http://www.biotechpharmacal.com makes Vitamin D3 in 5,000IU, 10,000IU & 50,000IU

    They are tiny, soft capsules that are very easy to swallow. If you don’t like capsules, cut them open and dissolve the powder in water.

    You can buy them here:

    Outside USA:


  2. Rita Celone Umile

    There is a school of thought that states that powdered vitamin D is better absorbed if dissolved in a spoonful of healthy fat–such as organic butter, or organic olive oil, or organic coconut oil.

  3. allometric24

    My cousin’s husband with long term MS in the UK has just been told by his specialist that they now recommend sufferers taking 5000 IU daily of D3.
    The NHS must be desperate! The horses have bolted.

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