Major depressive disorder (MDD) (also known as recurrent depressive disorder, clinical depression, major depression, unipolar depression, or unipolar disorder) is a mental disorder characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities.
The most common time of onset is between the ages of 20 and 30 years, with a later peak between 30 and 40 years.
Depressed individuals have shorter life expectancies than those without depression, in part because of greater susceptibility to medical illnesses and suicide.
There is increasing evidence that vitamin D affects all parts of the body, including the brain1. Thus, it is reasonable to think that having higher serum 25(OH)D levels would reduce the risk of depressive disorder.
Page last edited: 06 May 2011
- McCann, J. C. Ames, B. N. Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?. FASEB J. 2008 Apr; 22 (4): 982-1001.