- New study on the role of vitamin D in colon cancer
Colorectal cancerHow does vitamin D work?
A number of mechanisms have been identified by which vitamin D reduces the risk of colorectal cancer. These include effects such as regulation of cell growth, differentiation, apoptosis (programmed death) and a wide range of cellular mechanisms central to the development of cancer1 2, regulation of calcium absorption and metabolism3 4 5, and prevention of epithelial cell disjunction6.
Details of how colon cancer cells convert circulating 25(OH)D to 1,25-dihydroxyvitamin D3 [1,25(OH)2D] including the effects of (phyto)estrogens is discussed in a recent paper7.
Page last edited: 23 August 2011
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