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It is observed in Kerala ,in South India majority of the patients are having Vit D deficiency and related problems.It is observed that some of the patients are not responding to vit D therapy of 60000 K per week. Is there any possibility that these patients are allergic to Vit D so that the given Vit D is not absorbed …Is there any way to analyse this possibilty. Dr.Thomas George,Consultant Orthopaedic Surgeon

Asked by  drthomasanu19088100 on April 15, 2015

  •  drthomasanu19088100 on

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    Answered by  drthomasanu19088100 on
  •  IAW on

    If these patients are “obese” or very tall, they may need to take more than an average weight person.

    Do they take their Vitamin D with a meal or snack that has some amount of fat in it? It will absorb better. Do they have any kind of stomach/intestinal issues because that may cause malabsorption?

    Dr. Cannell once said “Keep in mind that body weight is only one of the factors that determine how much a given dose will increase your vitamin D levels.” “The main factor appears to be genetic.”

    He also said gastric bypass surgery and medications, such as glucocorticoids and anticonvulsants, can lower vitamin D levels. Low taurine levels in infants also decrease vitamin D absorption.

    “Metabolic clearance” of vitamin D if you are ill, or had surgery or exercise a lot has not been studied. So if they are ill they might be clearing it faster then what they are taking and therefore just need more.

    Dr. Cannell also said “If you are one of those people whose vitamin D levels will not go above 40 ng/ml, even on 10,000 units per day, and you won’t use sunlight or sunbeds, just keep increasing the dose up to 20,000 IU per day”.” “If that does not work, buy some coconut oil on the internet and add the contents of two 5,000 IU capsules of vitamin D to a tablespoon of coconut oil.” “Mix it well and then rub it into your skin every day, and see if that raises your vitamin D level.” Another person also said they had good luck with Vitamin D “oral spray” for better absorption on their patients.

    I hope you are also aware of the cofactors needed for Vitamin D http://www.vitamindcouncil.org/about-vitamin-d/vitamin-d-and-other-vitamins-and-minerals/. I assume you give them D3 and not D2. We also try and promote “daily” supplementation and maybe that would also help those that are having a hard time raising their levels.

    You can keep checking back to see if anyone else posts a suggestion!

    Answered by  IAW on

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