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I am curious as to the difference in absorption or efficacy of Vit D3 oral spray opposed to Vit D3 capsules? Is one form preferred over the other?

Asked by  Teresa on December 10, 2014

  •  Teresa on

    See title

    Answered by  Teresa on
  •  IAW on

    One form is not preferred over another. It is more important to have a reputable company making it so it is consistent from batch to batch. But below came from a blog member in April 2014:
    I normally recommend drops as they are the cheapest by a mile here in Ireland. I religiously check the blood levels after two months. About 20% of my clients have a poor response to the drops. When this happens I switch them to a sublingual spray which very quickly gets their levels up. It is a pity they did not test this dosage form.
    John Doran.
    Pharmacist, Naturopath, Herbalist.

    Answered by  IAW on
  •  Rebecca Oshiro on

    I had the privilege of assisting with this study at my university here in Seattle:


    They compared the effects of different forms of vitamin D supplements on blood levels of 25(OH)D and concluded: “Oil-emulsified vitamin D3 supplements resulted in a greater mean change in serum 25(OH)D concentration.”

    I personally use Biotech vitamin D3 capsules. They are competitively priced and I have no problems maintaining 25(OH)D levels in the 50-60 ng/mL range when taking 3,000 or 4,000 IU daily.

    Answered by  Rebecca Oshiro on
  •  Jeff Nicklas on


    IAW and Rebecca’s comments are spot on. The only real difference between capsules and sprays would be that sprays are absorbed directly into the cheeks on the inside of the mouth.

    For people with digestive issues, this may be helpful as the spray then bypasses the digestive system and goes right into the bloodstream.

    Answered by  Jeff Nicklas on

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