My wife is homozygous for vdr bsm, and has normal vdr taq. She has been taking 50,000 iu/wk. She has raised her vitamin d level to 35. She is now taking that amt every 4 days. Can someone with that SNP ever hope to achieve a level of 50? Or is it pointless to supplement? One more question, one of the headlines of your articles says resistance training increases vitamin d receptors. Is that true for someone with this defective vitamin d receptor SNP?