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Does vitamin D status relate to risk of premenstrual syndrome?

Posted on: June 9, 2014   by  Jeff Nicklas


A new study published in BMC Women’s Health reported mixed findings on the role of vitamin D in premenstrual syndrome.

The results suggest that higher vitamin D levels may increase the risk for premenstrual syndrome but that higher vitamin D levels may also decrease the risk for certain associated symptoms.

Premenstrual syndrome (PMS) is a disorder that occurs in women usually one to two weeks before menstruation and is characterized by a group of symptoms which include irritability, depression, breast tenderness, bloating, headaches, insomnia and changes in appetite. PMS occurs in 8-20% of premenopausal women and is common in women between the ages of 20 and 30 years old.

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2 Responses to Does vitamin D status relate to risk of premenstrual syndrome?

  1. [email protected]

    Only 0.3% of the women had PMS and happened to have a vitamin D blood test.
    Very roughly only 1 in 30 women with PMS happened to have a vitamin D blood test.
    Makes you wonder if the sampling was not just a bit biased.
    That and the fact that neither the PMS nor non PMS group had an even sub-optimal level of vitamin D makes one wonder about the validity of their observations and conclusions.

    Reminder: RCT several years ago found a single dose of vitamin D substantially reduced PMS
    None of the women getting the vitamin D needed ANY NSAID pain killers
    40% in placebo group needed NSAID pain killers at least once

  2. Rita and Misty

    Here I am–again: n=1.

    In my youth, my life was literally highjacked by my cycle.

    For half of the month I lived on Xanax. For five days out of the month, I lived on Xanax and Percocet .

    My moods were so completely subject to whatever day of the month it happened to be folks who knew me well enough also knew just when to avoid me.

    One marriage and several relationships ended over my PMS and painful menses. Even with Percocet, there were days I could not get out of bed.

    Since raising my 25(OH)D level to above 74 ng/ml, I am pain-free, and my mood is always sunny.

    Vitamin D has literally return to me my life.

    I suffered since age 11.

    It’s not much of a stretch to say I lost my entire youth to PMS and painful periods.

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