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Does tenofovir cause a “functional vitamin D deficiency”?

Posted on: September 9, 2013   by  Brant Cebulla


Researchers may have uncovered why the HIV drug tenofovir leads to bone loss and increased parathyroid hormone, and it may have something to do with vitamin D.

Tenofovir disoproxil fumarate is a prodrug of tenofovir and often used in combination with mantiretroviral therapy for patients with HIV. It is marketed under the trade name Viread.

The reason tenofovir is prescribed to HIV patients is because it lowers the amount of HIV in the blood, although there are no clinical trials showing that it can actually slow progression of HIV.

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2 Responses to Does tenofovir cause a “functional vitamin D deficiency”?

  1. Rebecca Oshiro

    This is an incredibly interesting piece. Will be sharing this blog with an HIV-positive friend.

  2. Brant Cebulla

    Thanks Rebecca. I found it interesting, too. I was a sucker for the phrase “functional vitamin D deficiency” in the title when literature searching. This is certainly some novel research.

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