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Different roles of vitamin D and activated D in treatment of chronic kidney disease

Posted on: February 14, 2012   by  John Cannell, MD


Chronic Kidney Disease (CKD) affects more than 16.0% of American adults aged 20 years and older, and is even higher among African Americans due, ostensibly to more severe hypertension in Blacks.

CKD presents initially without specific signs or symptoms and only blood tests can detect it by either an increase in serum creatinine or protein in the urine. As the kidney function decreases, creatinine goes up and the kidney spills more and more protein into the urine. In addition, as the disease progresses, blood pressure increases due to fluid overload and production of renin, further increasing hypertension or causing worsening congestive heart failure.

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