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Information on the latest vitamin D news and research.

Find out more information on deficiency, supplementation, sun exposure, and how vitamin D relates to your health.

Glucocorticoid users twice as likely to be deficient in vitamin D

About 1% of Americans are on glucocorticoids, usually for asthma or autoimmune diseases. These steroids lower inflammation, much like vitamin D, but do so at a cost in that people on glucocorticoids are more susceptible to a host of diseases, including infection and osteoporosis. So looking at vitamin D levels in people on glucocorticoids is important. We have some data from small studies that indicate patients on glucocorticoids have low vitamin D levels but no big population studies exist.

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About John Cannell, MD

Dr. John Cannell is founder of the Vitamin D Council. He has written many peer-reviewed papers on vitamin D and speaks frequently across the United States on the subject. Dr. Cannell holds an M.D. and has served the medical field as a general practitioner, emergency physician, and psychiatrist.
glucocorticoids

5 Responses to Glucocorticoid users twice as likely to be deficient in vitamin D

  1. Having read your articles on Asthma/VitD3, I decided to try increasing my daily dose(5000 IU
    at that time) to 10,000 IU daily for several months. Unfortunately this had no effect & so I have
    had to continue with the medication (Seretide 250[propionate de fluticasone salmeterol], 2 ‘puffs’
    per day, at the same time as reducing my VitD to 7,000IU (based on both my body weight & also
    blood levels)
    Regards
    Pamela Randolph

  2. whiteshepherd says:

    I have been taking vitamin d3 at 5000i.u. per day for approximately 6 months and paired this with magnesium citrate 6 weeks ago. I also inhale tiotropium 18mcg dry powder once daily together with budesonide/formoterol fumarate 400mcg/12 mcg dry powder twice daily to control asthma and COPD. Prior to commencing vitamin d3 I was using the steroid inhaler 4 and sometimes 5 times per day together with regular usage of terbutaline sulphate 500mcg as needed.

    It was my intention to publish full details of my vitamin d3 experience after 12 months but as you are asking for users of gluco-corticoids to respond to this blog I thought I would give my initial results to date prior to giving the complete 12 month picture.
    I live in West Cumbria UK close to the Lake District not particularly good for sunlight.

  3. Brant Cebulla says:

    Thanks for sharing guys. Pamela, do you get your 25(OH)D tested every once in awhile?

    whiteshepard, we’ll look forward to what you have to say down the road!

  4. DFM says:

    My 11 year old son has asthma and eczema. His pulmonologist initially prescribed Pulmicort as a preventative and Albuterol as a treatment if wheezing occurred and later substituted Advair for the Pulmicort. Over the past couple of years I have supplemented him daily with 5,000 IUs of Vitamin D, 2,300 mg of EDPA/DHA, and a probiotic. He no longer uses the Advair and needs the Alubuterol perhaps 5 times a year. He recently needed it but I believe that was simply because we were out of power for a week and had to use our wood burning fireplace. His Vit D level last checked was 54 ng/mL. His eczema is barely visible, if at all, and does not bother him. The short of it is he has significantly reduced his need for asthma medication but I suspect all three supplements have had a hand in his improvement.

  5. whiteshepherd says:

    A recent dried blood spot analysis gives the following result: 25(OH)D3 – 112.3 nmol/L.
    25(OH)D2 – 3.6 nmol/L. This on a maintained daily dose of 5000 iu over a 7 month period.
    Read in conjunction with my earlier posting.

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