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A new study shows vitamin D may help with pain and depression in women with type 2 diabetes

Posted on: December 4, 2013   by  Vitamin D Council


A new study out of Loyola University, Chicago, has shown that vitamin D may help alleviate pain and depression in women with type II diabetes.

People with type II diabetes (T2D) typically experience some level of pain and depression. To researchers’ interest, vitamin D deficiency has been linked to T2D, pain and depression, possibly explaining a link between the three to some degree.

Therefore researchers wanted to see if vitamin D could help alleviate depression and pain in those with T2D. So for six months, researchers gave depressed women with T2D a weekly vitamin D2 supplement of 50,000 IU.

Prior to the study, 61% of the women reported pain in their legs and feet, while 74% reported numbness and tingling in their hands, fingers and legs.

At the end of the trial, the researchers found that depression significantly improved with vitamin D supplementation. Additionally, they found a significant decrease in all reported areas of pain at both three and six months into the study.

“Vitamin D has widespread benefits for our health and certain chronic diseases such as type 2 diabetes,” said co-author, Dr. Sue Penckofer.

Upon completion of this study, the research team received a grant from the National Institute of Nursing Research to further their research by comparing different vitamin D doses on women with diabetes.

Dr. Todd Doyle, lead author of the study concluded, “While further research is needed, D2 supplementation is a promising treatment for both pain and depression in type 2 diabetes.”


Doyle, T. et al. Vitamin D Decreases Pain in Women with Type 2 Diabetes and Depression. Loyola Health Sciences, 2013.

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